Title: Cloudy alphabet soup: Case of warm autoantibody and a hidden surprise! 

Presenter: Megan Dupont, MLS(ASCP)^CMSBB^CM

Objectives:

• Interpret results of serologic tests in a case of warm autoantibody and underlying alloantibodies.
• Discuss methods to detect alloantibody in the presence of warm autoantibody.
• List options for transfusion of patients with warm autoantibody.

Level of Instruction: Intermediate

P.A.C.E. Contact Hours: 0.5

Title: Tackling those nebulous, troublesome, nuisance, interfering antibodies referred to as “high titer low avidity”

Presenter: Christine Lomas-Francis, MSc, FIBMS

Objectives:

• Discuss the concept of “high titer low avidity antibodies” (HTLA) and the blood groups associated with them.
• Describe methods used to differentiate such antibodies, including titration, neutralization and enzyme sensitivity.
• Describe the reactivity patterns associated with these antibodies and their clinical implications.

Level of Instruction: Intermediate

Title: Duffy phenotyping & genotyping as a diagnostic tool for benign constitutional neutropenia

Presenter: Gabriela de Toledo Passos Candelaria, MD

Objectives:

• Define neutropenia and discuss its possible causes and clinical consequences.
• Describe the Duffy Blood Group, including frequent phenotypes and polymorphisms.
• Discuss the use of Duffy phenotyping and/or genotyping in the diagnosis of benign consitutional neutropenia.

Level of Instruction: Intermediate

P.A.C.E. Contact Hours: 1.0

Title: High on glycophorins

Presenters: Eric Hebel, MLS(ASCP)^CM & Sunitha Vege, MS

Objectives:

• Describe serology tools used for investigating antibodies to high prevalence antigens, including adsorptions and chemical/enzyme treatments. 
• Discuss the diversity of the GYP locus. 
• Discuss the serology and current molecular testing strategies employed with altered GYP is suspected.

Level of Instruction: Advanced

P.A.C.E. Contact Hours: 1.0

Title: A mysterious case of FNAIT

Presenter: Shay Jones, MLS(ASCP)^CMBB^CM

Objectives:

• Discuss testing performed when FNAIT is suspected.
• Discuss common results for a case of FNAIT.
• Interpret results in an atypical case of FNAIT.

Level of Instruction: Intermediate

Title: In search of HLA compatible platelets

Presenter: Taba Kheradmand, PhD

Objectives:

• Explain the role of the HLA laboratory in selection of HLA compatible platelets.
• Discuss common challenges in selection of HLA compatible platelets.
• Describe ways to overcome challenges in selection of HLA compatible platelets. 

Level of Instruction: Intermediate

P.A.C.E. Contact Hours: 1.0

Title:  GECT: a new high prevalence antigen in the GE blood group system

Presenter: Toufik Tahiri, MS, MLS(ASCP)SBB^CM

Objectives:

• Discuss the GE (Gerbich) blood group system.
• Describe the general serological approach in resolving cases involving antibodies to high prevalence antigens.
• Explain the role of genomics in helping resolve complex antibody investigations.

Level of Instruction: Advanced

P.A.C.E. Contact Hours: 0.5