LFKRI Seminar Series
2022 Seminars
Monday, December 5, 2022 11:00 AM-12:00 PM
“Role of DNA damage stress in hematopoietic stem cell function”
Hans Snoeck, M.D., Ph.D.
Professor of Medicine
Director of Columbia Center for Stem Cell Therapies
Columbia University
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Tuesday, November 29, 2022 11:00 AM-12:00 PM
“The hematopoietic stem cell niche in beta-thalassemia: unraveling the role of bone defects and iron overload on stem cell function”
Annamaria Aprile, PhD
Project Leader, San Raffaele-Telethon
Institute for Gene Therapy (SR-Tiget), IRCCS
San Raffaele Scientific Institute, Milan, Italy
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Friday, November 18, 2022 11:00 AM-12:00 PM
“Epigenetic Memory of COVID-19 in Innate Immune Cells and Their Progenitors”
Dr. Steven Z. Josefowicz
Assistant Professor
Department of Pathology and Labratory Medicine, Division of Experimental Pathology Weill Cornwell Medicine
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Thursday, November 10, 2022 11:00 AM-12:00 PM
“Thinking Outside the Box of Acute and Chronic Viral Infections”
Guangxiang (George) Luo, MD, MPH
Endowed Professor in Infectious Diseases, Dept. of Microbiology
University of Alabama at Birmingham (UAB) School of Medicine
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Tuesday, November 8, 2022 11:00 AM-12:00 PM
“Engineered antibodies for targeted cytosolic delivery of proteins, red blood cells to overcome immunogenicity, and machine learning to predict cellular degradation of antigens”
Emery H. Bresnick, Ph.D.
Professor of Cell and Regenerative Biology
University of Wisconsin School of Medicine and Public Health, Wisconsin Institutes for Medical Research
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Wednesday, October 26, 2022 11:00 AM-12:00 PM
“Engineered antibodies for targeted cytosolic delivery of proteins, red blood cells to overcome immunogenicity, and machine learning to predict cellular degradation of antigens”
Bradley Pentelute, Ph.D.
Professor
Department of Chemistry, MIT, Associate Member, Broad Institute of MIT and Harvard
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Tuesday, October 25, 2022 11:00 AM-12:00 PM
“From ex vivo to in vivo targeting of HSC“
Stefano Rivella, Ph.D.
Professor of Pediatrics
Kwame Ohene-Frempong Chair on Sickle Cell Anemia, and Scientific Director of the Sickle Cell and Red Cell Disorders Curative Therapy Center (CuRED), Children’s Hospital of Philadelphia (CHoP)
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Friday, September 16, 2022 11:00 AM-12:00 PM
“Elucidating the origin of normal blood cells and the role of niche driving blood malignancies”
Jue Feng, Ph.D., (Faculty Recruit)
Associate Research Scientist
Department of Pathology, New York University Grossman School of Medicine
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Wednesday, September 14, 2022 11:00 AM-12:00 PM
“The myeloproliferative neoplasm (MPN): a model for clonal hematopoiesis and cardiovascular diseases”
Huichun Zhan, MD, MS, (Faculty Recruit)
Associate Professor
Stony Brook University, Attending Physicia, Northport VA Medical Center
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Monday, August 29, 2022 11:00 AM-12:00 PM
“Cellular crosstalk enables metabolic control of bacterial lung infection”
Xin Liu, Ph.D., (Faculty Recruit)
Postdoctoral Fellow
Department of Microbiology, University of Pennsylvania
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Tuesday, August 23, 2022 11:00 AM-12:00 PM
“Intrinsic and extrinsic regulation of hematopoietic stem cells in homeostasis and stress”
Ying Liang, MD, Ph.D.
Associate Professor
Department of Toxicology and Cancer Biology, Unviersity of Kentucky College of Medicine
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Monday, August 22, 2022 11:00 AM-12:00 PM
“Virus-host arms race: Translational regulation in the antiviral responses during SARS-CoV-2 infection”
Chun-Chieh (Jack) Hsu, Ph.D., (Facutly Recruit)
Postdoctoral Researcher
Department of Immunobiology, Yale University School of Medicine
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Tuesday, August 16, 2022 11:00 AM-12:00 PM
“Novel Mechanisms Underlying Inflammasome Signaling”
Venkat G. Magupalli, Ph.D., (Faculty Recruit)
Assistant Professor of Pediatrics, Boston Children’s Hospital, Havard Medical School
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Friday, August 12, 2022 10:30 AM-11:30 AM
“Blood Cell Trafficking in the Development of Inflammation of Thrombosis”
Bojing Shao, Ph.D., (Faculty Recruit)
Research Assistant Member
Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation
Tuesday, August 16, 2022 11:00 AM-12:00 PM
“Novel Mechanisms Underlying Inflammasome Signaling”
Venkat G. Magupalli, Ph.D., (Faculty Recruit)
Assistant Professor of Pediatrics, Boston Children’s Hospital, Havard Medical School
Monday, July 25, 2022 11:00 AM-12:00 PM
“Repurposing Tropical peptides for Biomedical Applications”
Junior Gonzales, Ph.D., (Faculty Recruit)
Research Associate
Radiology Department, Memorial Sloan Kettering Cancer Center
Tuesday, August 16, 2022 11:00 AM-12:00 PM
“Novel Mechanisms Underlying Inflammasome Signaling”
Venkat G. Magupalli, Ph.D., (Faculty Recruit)
Assistant Professor of Pediatrics, Boston Children’s Hospital, Havard Medical School
Thursday, June 23, 2022 11:00 AM-12:00 PM
“Invention to Venture”
Carl Berke, Ph.D.,
Partner, MGB Ventures
Tuesday, August 16, 2022 11:00 AM-12:00 PM
“Novel Mechanisms Underlying Inflammasome Signaling”
Venkat G. Magupalli, Ph.D., (Faculty Recruit)
Assistant Professor of Pediatrics, Boston Children’s Hospital, Havard Medical School
Tuesday, June 14, 2022 11:00 AM-12:00 PM
“Organelles In The Regulation of Hematopoiesis: Lessons from Mitochondria And Their Communications With Lyosomes”
Saghi Ghaffari, MD, Ph.D.,
Professor, Department of Cell Developmental and Regenerative Biology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Wednesday, May 25, 2022 12:00 PM-1:00 PM
“Interferon circuits in T cells and immunotherapy: a bedside to bench connection”
Jonathan Belman, MD, Ph.D.
Fellow in Transfusion Medicine and Theraputic Pathology Program, and the Laboratory of John Wherry, University of Pennyslvania
Tuesday, May 24, 2022 11:00 AM-12:00 PM
“Erythropoietin signaling in stress erythropoiesis”
Lily Huang, Ph.D.,
Associate Professor
Department of Cell Biology, University of Texas Southwestern Medical Center
Monday, April 25, 2022 11:00 AM-12:00 PM
“Activation of GPIb and VWF in thrombotic thrombocytopenia”
Renhao Li, Ph.D.
Professor of Pediatrics
Andrew K. Glaub Research Chair
Aflac Cancer & Blood Disorders Center
Children’s Healthcare of Atlanta/Emory University School of Medicine
Monday, April 11, 2022 11:00 AM-12:00 PM
“Gene Therapy in Sickle Cell Disease”
Julie Kanter, MD
Director, Adult Sickle Cell Program at the University of Alabama at Birmingham
Monday, February 21, 2022 12:00 PM-1:00 PM
“Adaptable vascular niche platform for stem cell self-renewal and organ regeneration”
Dr. Shahin Rafii
Arthur Belfer Professor of Genetic Medicine
Division Chief Regenerative Medicine
Director Hartman Institute for Therapeutic Organ Regeneration
Ansary Stem Cell Institute
Weill Cornell Medicine
Joseph M Scandura, MD, PhD
Associate Professor of Medicine
Weill Cornell Medical College
Tuesday, February 8 – 11 AM – 12 PM
“The role of EKLF/KLF1 in marking the erythroblastic island”
James Bieker, Ph.D.
Professor, Mount Sinai
Seminar Archive
Wednesday December 15th – 11 AM
“Discovering novel hematopoietic stem cell regulatory elements”
Antonio Morales-Hernandez, PhD (faculty recruit)
Postdoctoral Research Scholar, St. Jude Children’s Research Hospital
Tuesday December 7th -11 AM
“Sex differences in immune system aging and vaccine responses.”
Duygu Ucar, Ph.D.
Associate Professor, JAX Center For Aging Research , The Jackson Laboratory for Genomic Medicine
Wednesday December 1st – 11 AM
“Using Chemical Genetics to Define the Transcriptional Networks Controlled by Master Regulators of Hematopoiesis”
Scott Hiebert, PhD (faculty recruit)
Professor of Biochemistry and Hortense B. Ingram Chair in Cancer Research, Vanderbilt School of Medicine
Thursday November 18th – 11 AM
“Central tolerance and human immune system mice”
Nichole Danzl, PhD (faculty recruit)
Associate Research Scientist, and Director of the Human Studies Core, Columbia University
Tuesday November 16th – 11 AM
“Dysregulated Iron metabolism in Polycythemia Vera: Bench to Bedside”
Yelena Ginzburg, MD
Associate Professor, Department of Medicine, Icahn School of Medicine at Mount Sinai
Tuesday, October 12, 2021 – 11 AM
“ThPOKing Immune Cell Development and Function”
Jayati Basu, PhD, Research Assistant Professor, Fox Chase Cancer Center (faculty recruit)
Tuesday, October 5, 2021 – 11 AM
“Building tools to study normal and malignant hematopoietic precursors”
Jian Huang, MD, PhD (faculty recruit)
Associate Professor, Senior Scientist for Stem Cell Biology and Gene Engineering, Coriell Institute for Medical Research
Monday, September 27, 2021 – 11 AM
“Inflammation and barrier crosstalk in the pathophysiology of respiratory infections“
M. Nadeem Khan, PhD (faculty recruit)
Assistant Professor, School of Medicine and Health Sciences, University of North Dakota
Tuesday, September 21, 2021 – 10 AM
“Development of a Notch-Mediated Cell Expansion and Differentiation Platform for the Generation of Universal Donor Cord Blood Derived Cell Therapies.”
Colleen Delaney, MD
Chief Scientific Officer, Deverra Therapeutics, Inc., Clinical Professor, Division of Pediatric Hematology/Oncology, University of Washington/Seattle Children’s Hospital, Seattle
Monday, September 20, 2021 – 11 AM – 1 PM
“NK cells: next generation cell therapies for cancer”
Katy Rezvani, MD, PhD
Professor, Sally Cooper Murray Endowed Chair in Cancer Research, Director of Translational Research, Section Chief of Cellular Therapy, Department of Stem Cell Transplantation, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center
“Cord Blood: Forerunners and New Horizons”
Elizabeth J. Shpall, MD
Professor, Howard and Lee Smith Chair in Cancer Research and Director, Cord Blood Bank and Cell Therapy Laboratory, Department of Stem Cell Transplantation, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center
Monday, September 13, 2021 – 11 AM
“Rare cells, big effect: tuft cells in pulmonary inflammation”
Huachao Huang, PhD (faculty recruit)
Associate Research Scientist, Columbia University Medical Center
Tuesday, August 24, 2021 – 11 AM
“The role of mDia2 in terminal maturation of red blood cells”
Peng Ji, MD, PhD
Associate Professor, Department of Pathology, Northwestern University
August 12, 2021 – 12 PM
“Stem-cell derived human lung buds”
Edwin Rosado-Olivieri, PhD
Vice President, Rumi Viro
Thursday, April 23, 2020 – 12PM
“Audaces fortuna adjuvant – Designing and using next generation adjuvants for vaccines and immunotherapies”
Darrick Carter Ph.D.
CEO, PAI Life Sciences Inc., Affiliate Professor, School of Medicine, Medical Genetics, University of Washington
POSTPONED TO LATER DATE
“Resolution of inflammation depends on Nuclear Receptor Nur77”
Carlie JM de Vries, PhD
Professor and Chair Department of Medical Biochemistry, Amsterdam University Medical Center, The Netherlands
POSTPONED TO LATER DATE
“The role of mDia2 in terminal maturation of red blood cells”
Peng Ji, MD, PhD
Associate Professor, Department of Pathology, Director, Pathology Physician-Scientist Training Program, Northwestern University.
Thursday, February 27, 2020 – 11AM
“When Epigenetics Meet Metabolism in Hematopoiesis”
Jian Xu, PhD
Associate Professor, Children’s Research Institute, UT Southwestern Medical Center
Thursday, February 13, 2020 – 11AM
“Beating swords into plowshares: the use of Fc receptor modification to develop a neutrophil extracellular trap targeted therapy for the treatment of sepsis”
Kandace Gollomp, MD
Instructor, Department of Pediatrics, Attending Physician, Division of Hematology, Children’s Hospital of Philadelphia
Thursday, December 19, 2019 – 11AM
“Global Aspects in Cellular Therapy: Standards, Science & Unproven Therapies”
Joseph Schwartz, MD, MPH
Director, Transfusion Medicine Services, Professor of Pathology & Cell Biology, Columbia University Medical Center
Thursday, October 24, 2019 — 11AM
“Pathophysiological consequences of iron overload: lesson from a mouse model of type IV hereditary hemochromatosis
Sandro Altamura, PhD
Post-doctoral Fellow, University of Heidelberg and European Molecular Biology Laboratory (EMBL), Germany
Wednesday, October 2, 2019 – 10AM
“From epidemiology to single-cell analysis: recent insights into malaria and sickle cell disease”
Bronner Goncalves, MD, MPH, PhD
Bioinformatics Scientist, National Institutes of Health and Medical Science & Computing, LLC
Tuesday, September 24, 2019 – 11AM
“The 100,000 Genomes Project: New Genes for Rare Blood Diseases”
Willem H. Ouwehand, MD, PhD
Professor of Experimental Hematology, University of Cambridge
Tuesday, August 20, 2019 – 11AM
“Banking With Precision: Predicting Red Blood Cell Phenotypes from Next Generation Sequencing Data”
Celina Montemayor, MD, PhD
Staff Clinician, Assistant Clinical Investigator, Department of Transfusion Medicine, National Institutes of Health Clinical Center
Tuesday, June 18, 2019 – 1PM
“Characterizing Social Support Within the Sexual Networks of Gay Men: Implications for HIV Prevention Strategies”
Jorge H. Soler, PhD, MPH
Postdoctoral Fellow, HIV Center for Clinical and Behavioral Studies, Columbia University & New York State Psychiatric Institute
Wednesday, May 8, 2019 –1PM
“Old Pathways and New Players in Anemia of Chronic Disease and Diamond Blackfan Anemia”
Lionel Blanc, PhD
Associate Professor of Molecular Medicine and Pediatrics, The Feinstein Institute for Medical Research, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
Friday, March 22, 2019 – 11AM
“SARS and MERS coronaviruses: cross-species transmission and vaccine design”
Fang Li, PhD
Associate Professor, Dept Veterinary andBiomedical Sciences, University of Minnesota Twin Cities
Wednesday, January 30, 2019 – 10AM
“Molecular Drivers of Platelet Production”
Joseph Italiano, PhD
Associate Professor of Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston Children’s Hospital
Wednesday, December 12, 2018 – 10AM
“Mitochondrial Dynamics and Intracellular Calcium Signaling Regulate Hematopoietic Stem Cell Function”
Larry Luchsinger, PhD
Associate Research Scientist, Department of Medicine, Columbia University Medical Center
Thursday, November 1, 2018 – 10AM
“3D Bone Marrow modelling to document megakaryocyte functional regulation and diseases”
Alessandra Balduini, MD
Associate Professor, University of Pavia, Italy; Research Associate Professor, Tufts University, Boston, MA
Thursday, October 18, 2018 – 11AM
“In vitro studies of erythropoiesis”
Ashley Toye, PhD
Principal Investigator, UK NHS-Blood & Transplant, and Senior Lecturer in Erythrocyte Biology, Department of Biochemistry, University of Bristol, UK
Thursday, October 11, 2018 – 11AM
“Thrombopoietic Agents in 2018: Ten Years Later”
James Bussel, MD
Professor Emeritus of Pediatrics, Weill Cornell Medical School, New York
Thursday, October 4, 2018 – 11AM
“Exploring the role of TAM (Tyro3_Axl_Mertk) receptors as a novel innate immune checkpoint in cancer immunotherapy”
Hind Medyouf, PhD
Group Leader, Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt am Main, Germany
Thursday, September 13, 2018 – 11:30AM
“Blood Center Considerations for Cellular Product Collections and Distribution”
Robert J. Tressler PhD
Vice President of Laboratories at San Diego Blood Bank
Thursday, September 6, 2018 – 11AM
“Modeling HIV pathogenesis, prevention and novel therapies in humanized mice”
Ramesh Akkina, DVM, PhD
Professor, Department of Microbiology, Immunology and Pathology, Colorado State University
Wednesday, August 29, 2018 – 1PM
“Setting up biobanks and translation research services in academia; experiences and challenges”
Hassana Fathallah, PhD
Director, Clinical Trials Scientific Affairs, ACM Global Laboratories, Rochester, New York
WEDNESDAY, AUGUST 22, 2018 – 1PM
“The role of CDMO’s in the commercialization of cell therapy“
Ruud Hulspas, PhD
Founder, Cellular Technologies Bio-consulting, LLC, Rockville, MD
MONDAY, JULY 9, 2018 – 11AM
“Pulmonary Inflammation in Sickle Cell Disease”
Jeffrey A. Glassberg, M.D.
Associate Professor of Hematology and Medical Oncology, and Emergency Medicine, Mount Sinai School of Medicine, New York
THURSDAY, JUNE 14, 2018 – 11AM
“Apheresis Collection for T cell Manufacturing: What’s in the bag and why do we care?”
Andrew D. Fesnak, MD
Assistant Professor, Director, Manufacturing, Clinical Cell and Vaccine Production Facility, University of Pennsylvania
FRIDAY, APRIL 20, 2018 – 12PM
“Patient Blood Management in Sickle Cell Disease”
France Pirenne, MD, PhD
Medical and Scientific Director, Etablissement Français du Sang, Créteil, Professor of Hematology, Institut Mondor de Recherche Biomédicale, lNSERM
FRIDAY, MARCH 30, 2018 – 11AM
“Barriers and Facilitators to Potential Future Biomedical HIV Prevention Products in Transgender and Cisgender Women”
Christine Rael, PhD
Postdoctoral Research Fellow, HIV Center for Clinical and Behavioral Studies, Columbia University
THURSDAY, FEBRUARY 22, 2018 – 11AM
“Role of Tissue Factor in Hemostasis, Thrombosis and Viral Infections”
Nigel Mackman, PhD, FAHA
John C. Parker
Distinguished Professor of Medicine, Co-Director of the Thrombosis and Hemostasis Program, University of North Carolina at Chapel Hill
MONDAY, DECEMBER 4, 2017 – 11AM
“Armored Chimeric Antigen Receptor (CAR) T Cells for Solid Tumor Malignancies”
Oladapo Yeku, MD, PhD
Medical Oncology Fellow, Memorial Sloan Kettering Cancer Center
THURSDAY, NOVEMBER 30, 2017 – 11AM
“Type 1 Interferons Promote Alloimmune Responses to Transfused RBC Antigens”
David Gibbs, MD, PhD
Transfusion Medicine/Blood Bank Fellow, Department of Laboratory Medicine, Yale University
TUESDAY, NOVEMBER 28, 2017 – 11AM
“Stem Cell-Derived Megakaryocytes Tool for Translational Research and Source of Cellular Therapies”
Camelia Iancu-Rubin, PhD
Associate Professor, Scientific Director, Hematological Malignancies Tissue Bank, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
MONDAY, NOVEMER 20, 2017 – 11AM
“Investigations into the AML Cell Surfaceome”
Fabiana Perna, MD, PhD
Senior Research Scientist, Memorial Sloan Kettering Cancer Center, New York
THURSDAY, November 16, 2017 – 11AM
“Insights into Immune Defects in Rag-deficiency and Stem Cell Collections for Gene Therapy in Sickle Cell Anemia”
John Manis, MD
Associate Director of Transfusion Medicine, Boston Children’s Hospital, Harvard Medical School
THURSDAY, OCTOBER 12, 2017 – 11AM
“Heterogeneity Assays and Platelet Lysate: Challenges and Chances for Stem Cell Therapies Development”
Richard Schaefer, MD
Head of Department Cell Therapeutics & Cell Processing, German Red Cross, Goethe-University Hospital, Frankfurt, Germany
THURSDAY, SEPTEMBER 7, 2017 – 11AM
“Exploring the Human Microbiome”
Tao Ding, PhD
Postdoctoral Researcher, Department of Biology, Center for Genomics and Systems Biology, New York University
MONDAY, AUGUST 21, 2017 – 11AM
“Inflammasomes and Danger Signals during Infection by Intracellular Pathogens”
David M. Ojcius, PhD
Professor and Chair, Department of Biomedical Sciences, University of the Pacific,Arthur A. Dugoni School of Dentistry
MONDAY, JULY 24, 2017 – 2PM
“Inflammatory Modulation of the Bone Marrow Hematopoietic Niche”
Leslie E. Silberstein, MD
Director, Joint Program in Transfusion Medicine, Professor, Harvard Medical School
THURSDAY, JULY 20, 2017 – 11AM
“Dickkopf-1: The Wnt Antagonist Becomes a Novel Immunomodulator”
Wook-Jin Chae, PhD
Associate Research Scientist, Department of Immunobiology, Yale University School of Medicine
MONDAY, JULY 17, 2017 – 1PM
“Making Platelets In Vitro from Pluripotent Stem Cells: Going Beyond Transfusion and Blood Clotting”
Cedric Ghevaert, MD, PhD
Consultant Hematologist, Senior Lecturer in Transfusion Medicine, Department of Hematology, University of Cambridge, UK
THURSDAY, MAY 18, 2017 – 11AM
“The Mechanism of Action of Anti-D in Preventing Hemolytic Disease of the Fetus and Newborn: What Do We Really Know?”
Alan H. Lazarus, PhD
Scientist, St. Michael’s Hospital and Canadian Blood Services, Professor of Medicine, University of Toronto
WEDNESDAY, APRIL 5, 2017 – 1PM
“Genetics and Metabolomics of Blood Storage”
James C. Zimring, MD, PhD
Director and Chief Scientific Officer, BloodworksNW Research Institute, Professor, Department of Lab Medicine and Department of Medicine, University of Washington School of Medicine
THURSDAY, MARCH 2, 2017 – 11AM
“Insights into ZIKV Epidemiology, Diagnostics and Pathogenesis from Studies of Blood Donors and Recipients”
Michael Busch, MD, PhD
Director and VP, Research and Scientific Affairs, Blood Systems Research Institute
THURSDAY, FEBRUARY 16, 2017 – 11AM
“Engineering of Complex Tissues – New Possibilities for Drug Development and Regenerative Medicine”
Jan Hansmann, PhD
Group Leader, University Hospital of Würzburg, Fraunhofer Institute of Interfacial Engineering and Biotechnology
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